Tuberculosis

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Archived News and Updates

In a PLoS Pathogens article entitled, "The Past and Future of Tuberculosis Research" Inaki Comas and Sebastien Gagneux argue that new multidisciplinary approaches, especially those that integrate epidemiology with systems biology in what they call "systems epidemiology," will be required to eliminate TB.
The Stop TB Partnership's New Diagnostics Working Group (NDWG) has launched a new website resource called Evidence-based Tuberculosis Diagnosis. The main objective of the new website is to provide the most comprehensive single source of evidence syntheses, policies, guidelines and research agendas on TB diagnosis. It addresses a long-standing need for a single portal that compiles all critical evidence on TB diagno sis, with relevant policies and guidelines for clinicians and public health professionals.
TB's return comes with high costs: You might think tuberculosis hasn't been a problem since your grandparent's era, but the illness is making a worldwide comeback. Its costs of treatment and lost productivity are estimated at almost $3 billion a year. Listen to Frank Browning reports on NPR's Market Place.
Patients with inadequately treated multidrug resistant (MDR TB) are more infective than others. A study by Escombe et al. finds a small number of inadequately treated MDR TB patients coinfected with HIV were responsible for almost all TB transmission, and some patients were highly infectious. This study highlights the importance of rapid TB drug-susceptibility testing to allow prompt initiation of effective treatment, and environmental control measures to reduce ongoing TB transmission in crowded health care settings.
Aggressive TB treatment a success: Tuberculosis which is resistant to many current treatments can be overcome with aggressive therapy, research suggests.
The New England Journal of Medicine: More than 60 percent of patients diagnosed with extensively drug-resistant TB (XDR-TB), a type of tuberculosis that is very difficult to treat were cured with aggressive drug treatment by a team of Peruvian doctors.
Genome Research: Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
Association calls on state to fund tb programs In recognition of World TB Day on March 24, the American Lung Association of California released troubling statewide tuberculosis (TB) statistics and called on the state to avert a resurgence of TB by funding prevention and control efforts.
Sequencing of XDR TB: Work of South Africa-US research team gives first look at genome of XDR TB from KZN outbreak. Initial analysis highlights small number of DNA differences among drug-resistant and -sensitive microbes.
PLos Pathogens: Mycobacterium tuberculosis nuoG Is a Virulence Gene That Inhibits Apoptosis of Infected Host Cells.
Elsevier Tuberculosis Journal: Browse or search for articles in the current issue.
Search PubMed for articles related to Tuberculosis.
World Health Organization provides information about Tuberculosis for clinicians and public health workers.
US Centers for Disease Control and Prevention (CDC) provides news and updates about Tuberculosis.